See section 1.4 for general contraindications for all vaccines.
BCG vaccine should not be given to individuals:
receiving corticosteroids or other immunosuppressive treatment, including radiotherapy (see section 4.3)
suffering from malignant conditions such as lymphoma, leukaemia, Hodgkin’s disease or other tumours of the reticulo-endothelial system
in whom an immune-compromising disease is known or suspected, such as individuals with hypogammaglobulinaemia – primary immune deﬁciencies in children are often not detected until after the ﬁrst few weeks of life (ie, after BCG vaccine is given), so a family history of immune deﬁciency should be sought and, if present, discussed with a paediatrician before vaccination
known to be infected with HIV, including neonates where the mother’s HIV status is unknown – maternal HIV infection should be excluded prior to neonatal vaccination; testing should have been offered as part of the National Antenatal HIV Screening Programme, and infants born to HIV-infected mothers should be under the care of a paediatrician
aged under 8 months, whose mothers took anti-tumour necrosis factor (anti-TNF) therapies (eg, infliximab) during pregnancy – BCG vaccination should be delayed until the infant is at least 8–9 months old;23 these drugs may cross the placenta and cause immunosuppression in the infant
with a positive tuberculin skin test reaction or who have a positive IGRA