22 Zoster (herpes zoster/shingles)

22.1 Virology

Varicella-zoster virus (VZV) is a DNA virus from the herpesvirus family. Primary infection with VZV causes varicella zoster disease (chickenpox). Herpes zoster (HZ) or ‘shingles’, is a clinical syndrome caused by reactivation of latent VZV, which resides in the dorsal root or trigeminal nerve ganglia following primary infection.