See section 14.7 for expected responses and adverse events following immunisation with DTaP-IPV-HepB/Hib vaccine.
Adverse reactions to Hib conjugate vaccines are uncommon. Pain, redness and swelling at the injection site occur in approximately 25 percent of recipients, but these symptoms typically are mild and last less than 24 hours.11
A meta-analysis of trials of Hib vaccination from 1990 to 1997 found that serious adverse events were rare.12 No serious vaccine-related adverse experiences were observed during clinical trials of Hib vaccine alone. There have been rare reports, not proven to be causally related to Hib vaccine, of erythema multiforme, urticaria, seizures and Guillain-Barré Syndrome.13